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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0660-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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| RCP0660-10 | 7 days | 10 µg | $290.00 | |||
| RCP0660-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | DNAJC12 Human |
|---|---|
| Description | |
| DnaJ (Hsp40) Homolog, Subfamily C, Member 12 Human Recombinant | |
| Accession (Primary) | Q9UKB3 |
| Synonyms | |
| DnaJ homolog subfamily C member 15, Cell growth-inhibiting gene 22 protein, Methylation-controlled J protein, MCJ, DNAJC15, DNAJD1, GIG22, HSD18. | |
| Introduction | |
| DNAJC15 which is expressed ubiquitously and located on the membrane contains 1 J domain. In many advanced cases of ovarian adenocarcinoma DNAJC15 is absent or down-regulated, due to hypermethylation and allelic loss. Loss of expression correlates with increased resistance to antineoplastic drugs, such as cisplatin. DNAJC15is a crucial component of the TIM23 translocase complex and stimulates the ATPase activity of HSPA9. | |
| Source | |
| E.coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The DNAJC15 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 0.15M NaCl, 20% glycerol and 1mM DTT. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS FRIWKPL EQVITETAKK ISTPSFSSYY KGGFEQKMSR REAGLILGVS PSAGKAKIRT AHRRVMILNH PDKGGSPYVA AKINEAKDLL ETTTKH. | |
| Precautions | |
| DNAJC12 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9UKB3 ) | |
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ADMEbio Team
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