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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0732-1 | 7 days | 1 µg | $120.00 |
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| RCP0732-5 | 7 days | 5 µg | $290.00 | |||
| RCP0732-50 | 7 days | 50 µg | $1,920.00 |
Product Overview | |
| Name | EIF2B1 Human |
|---|---|
| Description | |
| Eukaryotic Translation Initiation Factor 2B Subunit 1 Alpha Human Recombinant | |
| Accession (Primary) | Q14232 |
| Immunogen | |
| Anti-human EIF2S1 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human EIF2S1 amino acids 1-315 purified from E. coli. | |
| Synonyms | |
| Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, EIF-2alpha, EIF-2A, EIF2, EIF-2, EIF2A, EIF-2A. | |
| Introduction | |
| EIF2S1 participates in the premature steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA which binds to a 40S ribosomal subunit, followed by mRNA binding to create a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 should exchange with GTP by way of a reaction catalyzed by eIF-2B. | |
| Formulation | |
| 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. | |
| Applications | |
| EIF2S1 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| PEIF2S1AT. | |
| Ig Subclass | |
| Mouse IgG 2b heavy chain and kappa light chain. | |
| Purification Method | |
| EIF2S1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. | |
| Storage Procedures | |
| For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
| Stability / Shelf Life | |
| 12 months at -20°C. 1 month at 4°C. | |
| Precautions | |
| EIF2B1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q14232 ) | |
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ADMEbio Team
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ADMEbio Team
