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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0747-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP0747-20 | 7 days | 20 µg | $290.00 | |||
| RCP0747-1 | 7 days | 1 mg | $5,760.00 |
Product Overview | |
| Name | EIF5A Human |
|---|---|
| Description | |
| Eukaryotic Translation Initiation Factor 5A Human Recombinant | |
| Accession (Primary) | P63241 |
| Synonyms | |
| eIF-5A-2, EIF-5A2, eIF5AII, Eukaryotic translation initiation factor 5A-2, Eukaryotic initiation factor 5A isoform 2, EIF5A2. | |
| Introduction | |
| EIF5A2 is part of the eukaryotic initiation factor 5A subfamily, is an vital protein strongly linked to cellular polyamine homeostasis. EIF5A2 promotes the formation of the first peptide bond during the initial stage of protein synthesis. EIF5A2 is the single eukaryotic protein to have a hypusine residue, which is a post-translational modification of a lysine by the addition of a butylamino group. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| EIF5A2 Human solution containing 20mM Tris-HCl pH-8 & 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 85.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MADEIDFTTG DAGASSTYPM QCSALRKNGF VVLKGRPCKI VEMSTSKTGK HGHAKVHLVG IDIFTGKKYE DICPSTHNMD VPNIKRNDYQ LICIQDGYLS LLTETGEVRE DLKLPEGELG KEIEGKYNAG EDVQVSVMCA MSEEYAVAIK PCK. | |
| Precautions | |
| EIF5A Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P63241 ) | |
References |
Title: Inhibition of Deoxyhypusine Synthase Enhances Islet b Cell Function and Survival in the Setting of Endoplasmic Reticulum Stress and Type 2 Diabetes Publication: Journal of Biological Chemistry 285.51 (2010): 39943-39952. Link: EIF5A prospec publication |
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ADMEbio Team
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