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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0750-10 | 7 days | 10 µg | $120.00 |
Select product before adding to cart
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| RCP0750-50 | 7 days | 50 µg | $290.00 | |||
| RCP0750-1 | 7 days | 1 mg | $2,880.00 |
Product Overview | |
| Name | ELOB Human |
|---|---|
| Description | |
| Elongin-B Polypeptide 2 Human Recombinant | |
| Accession (Primary) | Q15370 |
| Synonyms | |
| Transcription elongation factor B polypeptide 2, TCEB2, RNA polymerase IItranscription factor SIII subunit B, SIII p18, EloB, Elongin 18 kDa subunit. | |
| Introduction | |
| Elongin B (Elob) is a subunit of the transcription factor B (SIII) complex. SIII complex is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. The SIII complex comprised of a transcriptionally active subunit (A) and 2 regulatory subunits (B and C). Subunit A is transcriptionally active and its transcription activity is enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C. The von Hippel-Lindau tumor suppressor protein binds to elongin B and C and inhibits transcription elongation. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| The protein (1mg/ml) contains PBS pH-7.4 containing 1mM DTT and 10% Glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGSMDVFLMI RRHKTTIFTD AKESSTVFEL KRIVEGILKR PPEEQRLYKD DQLLDDGKTL GECGFTSQTA RPQAPATVGL AFRADDTFEA LRIEPFSSPP ELPDVMKPQD SGGSANEQAV Q | |
| Precautions | |
| ELOB Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q15370 ) | |
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ADMEbio Team
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ADMEbio Team
