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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0761-2 | 7 days | 2 µg | $120.00 |
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| RCP0761-10 | 7 days | 10 µg | $290.00 | |||
| RCP0761-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | EPCAM Human, sf9 |
|---|---|
| Description | |
| Epithelial Cell Adhesion Molecule Human Recombinant, Sf9 | |
| Accession (Primary) | P16422 |
| Synonyms | |
| EPG, Epigen, PRO9904, ALGV3072, FLJ75542, EPGN, Epithelial mitogen. | |
| Introduction | |
| EPGN is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. EPGN is produced in numerous tissues, including the testis, liver, heart and in certain tumor cells. EPGN is mitogenic for fibroblasts and epithelial cells. Human EPGN is originally synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| EPGN was lyophilized from 20mM PBS buffer pH-7.4 . | |
| Stability | |
| Lyophilized Epigen although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution EPGN should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| AVTVTPPITA QQADNIEGPI ALKFSHLCLE DHNSYCINGA CAFHHELEKA ICRCFTGYTG ERCEHLTLTS YA | |
| Biological Activity | |
| Determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells. The expected ED 50 for this effect is less than 300 ng/ml, corresponding to a specific activity of > 3.3 ×103 IU/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Epigen in sterile 18MΩ-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| EPCAM Human, sf9 is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P16422 ) | |
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