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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0765-1 | 7 days | 1 µg | $120.00 |
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| RCP0765-5 | 7 days | 5 µg | $290.00 | |||
| RCP0765-50 | 7 days | 50 µg | $1,920.00 |
Product Overview | |
| Name | EPHA4 Mouse |
|---|---|
| Description | |
| EPH Receptor A4 Mouse Recombinant | |
| Accession (Primary) | Q03137 |
| Synonyms | |
| EPHB-1, Ephrin type-B receptor 1, Eph Receptor B1, ELK, EPH tyrosine kinase 2, EPH-like kinase 6, EK6, hEK6, HEK6, Neuronally-expressed EPH-related tyrosine kinase, NET, NETHek6, Tyrosine-protein kinase receptor EPH-2, EPHT2, soluble EPHB1 variant 1 | |
| Introduction | |
| EPH Receptor B1 (EPHB1) is a member of the ephrin receptor subfamily of the proteintyrosine kinase family which 16 receptors are known. EPHB1 binds ephrin-B2, ephrin-B1,ephrin‑A3,ephrin-A1,ephrin-B3 and ephrin-A4. EPHB1 binds tyrosine kinase and phosphorylates syndecan-2 and thisphosphorylation is necessary for syndecan-2 clustering and spine formation. Ephrin receptors and theirligands (the ephrins) mediate several developmental processes, mainly in the nervous system. | |
| Source | |
| HEK293 Cells. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| The EPHB1 solution (0.25mg/1ml) contains phosphate buffered saline (pH7.4) and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MEETLMDTRT ATAELGWTAN PASGWEEVSG YDENLNTIRT YQVCNVFEPN QNNWLLTTFI NRRGAHRIYT EMRFTVRDCS SLPNVPGSCK ETFNLYYYET DSVIATKKSA FWSEAPYLKV DTIAADESFS QVDFGGRLMK VNTEVRSFGP LTRNGFYLAF QDYGACMSLL SVRVFFKKCP SIVQNFAVFP ETMTGAESTS LVIARGTCIP NAEEVDVPIK LYCNGDGEWM VPIGRCTCKP GYEPENSVAC KACPAGTFKA SQEAEGCSHC PSNSRSPAEA SPICTCRTGY YRADFDPPEV ACTSVPSGPR NVISIVNETS IILEWHPPRE TGGRDDVTYN IICKKCRADR RSCSRCDDNV EFVPRQLGLT ECRVSISSLW AHTPYTFDIQ AINGVSSKSP FPPQHVSVNI TTNQAAPSTV PIMHQVSATM RSITLSWPQP EQPNGIILDY EIRYYEKEHN EFNSSMARSQ TNTARIDGLR PGMVYVVQVR ARTVAGYGKF SGKMCFQTLT DDDYKSELRE QLP HHHHHH | |
| Biological Activity | |
| Measured by its binding ability in a functional ELISA with Human EFNB1 (cat# pro-2543). | |
| Precautions | |
| EPHA4 Mouse is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q03137 ) | |
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ADMEbio Team
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