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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0790-5 | 7 days | 5 µg | $120.00 |
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| RCP0790-20 | 7 days | 20 µg | $290.00 | |||
| RCP0790-1 | 7 days | 1 mg | $5,760.00 |
Product Overview | |
| Name | EXOSC4 Human |
|---|---|
| Description | |
| Exosome Component 4 Human Recombinant | |
| Accession (Primary) | Q9NPD3 |
| Synonyms | |
| Exosome component 5, Chronic myelogenous leukemia tumor antigen 28, Ribosomal RNA-processing protein 46, exosome complex exonuclease RRP46, RRP41B, hRrp46p, CML28, p12B. | |
| Introduction | |
| EXOSC5 is a member of the RNase PH family. EXOSC5 is known to cooperate with Exosome component 8 and Exosome component 1. EXOSC5 is a Non-catalytic component of the RNA exosome complex and has 3'->5' exoribonuclease activity. EXOSC5 take part in a large number of cellular RNA processing and degradation events. EXOSC5 is expressed in a large range of hematopoietic and epithelial tumor cell lines, but not in standard hematopoietic tissues or other standard tissue, with the exception of testis. | |
| Source | |
| E.coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The EXOSC5 solution (0.5mg/1ml) contains PBS buffer (pH 7.4), 200mM Nacl, 2mM DTT and 30% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH M MEEETHTDA KIRAENGTGS SPRGPGCSLR HFACEQNLLS RPDGSASFLQ GDTSVLAGVY GPAEVKVSKE IFNKATLEVI LRPKIGLPGV AEKSRERLIR NTCEAVVLGT LHPRTSITVV LQVVSDAGSL LACCLNAACM ALVDAGVPMR ALFCGVACAL DSDGTLVLDP TSKQEKEARA VLTFALDSVE RKLLMSSTKG LYSDTELQQC LAAAQAASQH VFRFYRESLQ RRYSKS | |
| Precautions | |
| EXOSC4 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9NPD3 ) | |
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ADMEbio Team
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ADMEbio Team
