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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0807-2 | 7 days | 2 µg | $120.00 |
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| RCP0807-10 | 7 days | 10 µg | $290.00 | |||
| RCP0807-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | FABP12 Human |
|---|---|
| Description | |
| Fatty Acid Binding Protein-12 Human Recombinant | |
| Accession (Primary) | A6NFH5 |
| Synonyms | |
| Fatty acid-binding protein 2, IFABP, I-FABP, FABPI, FABP-2, Fatty acid-binding protein intestinal, FABP2, MGC133132. | |
| Introduction | |
| FABP multigene family has almost 20 known members. FABPs are divided into 3 different types: hepatic, intestinal and cardiac which form 14-15 kDa proteins that take part in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. FABPs are involved in the modulation of cell growth and proliferation. Intestinal FABP (FABP2) gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and resistance. High serum levels of FABP2 is ulcerative colitis indicates ileitis. FABP2 is has part in triglyceride-rich lipoprotein synthesis. FABP2 binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 helps maintain energy homeostasis by functioning as a lipid sensor. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| FABP2 was lyophilized from a 0.2 µm filtered concentrated solution in 1xPBS, pH7.4. | |
| Stability | |
| Lyophilized FABP2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FABP2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| AFDSTWKVDR SENYDKFMEK MGVNIVKRKL AAHDNLKLTI TQEGNKFTVK ESSAFRNIEV VFELGVTFNY NLADGTELRG TWSLEGNKLI GKFKRTDNGN ELNTVREIIG DELVQTYVYE GVEAKRIFKK D. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Interleukin FABP2 in sterile 18M-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| FABP12 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( A6NFH5 ) | |
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