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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0825-50 | 7 days | 50 µg | $400.00 |
Select product before adding to cart
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| RCP0825-100 | 7 days | 100 µg | $600.00 | |||
| RCP0825-1 | 7 days | 1 mg | $2,400.00 |
Product Overview | |
| Name | FAM111B Human |
|---|---|
| Description | |
| Family with Sequence Similarity 111, Member B Human Recombinant | |
| Accession (Primary) | Q6SJ93 |
| Synonyms | |
| Family With Sequence Similarity 19 (Chemokine (C-C Motif)-Like), Member A5, Chemokine-Like Protein TAFA-5, TAFA5, TAFA Protein 5, QLLK5208, UNQ5208, TAFA-5, FAM19A5. | |
| Introduction | |
| Family With Sequence Similarity 19 Member-A5 (FAM19A5) belongs to the TAFA family which is comprised of 5 highly homologous genes encoding small secreted proteins. These proteins have conserved cysteine residues at fixed positions, and are remotely related to MIP-1alpha, which is a member of the CC-chemokine family. The TAFA proteins are primarily expressed in specific regions of the brain, and are assumed to serve as brain-specific chemokines or neurokines which act as regulators of immune and nervous cells. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Filtered colorless solution. | |
| Formulation | |
| FAM19A5 filtered (0.4 µm) solution in 20mM Tris buffer, 50mM NaCl, pH 7.5 and 10% (w/v) glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MKHHHHHHAS QFLKEGQLAA GTCEIVTLDR DSSQPRRTIA RQTARCACRK GQIAGTTRAR PACVDARIIK TKQWCDMLPC LEGEGCDLLI NRSGWTCTQP GGRIKTTTVS. | |
| Precautions | |
| FAM111B Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q6SJ93 ) | |
Background |
Family with Sequence Similarity 111 Member B (FAM111B) is a part of the FAM111 gene family which participates in cellular processes such as cell cycle regulation, DNA replication and maintenance of genomic stability. FAM111B is a protein-coding gene located on human chromosome 10. FAM111B function is linked to its interactions with other cellular machinery that ensures the fidelity of DNA replication and the repair of DNA damage. FAM111B has conserved domains which may be critical for its interactions with other proteins involved in DNA repair and replication. |
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