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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0884-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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| RCP0884-10 | 7 days | 10 µg | $290.00 | |||
| RCP0884-100 | 7 days | 100 µg | $1,920.00 |
Product Overview | |
| Name | FZD10 Human |
|---|---|
| Description | |
| Frizzled Class Receptor 10 Human Recombinant | |
| Accession (Primary) | Q9ULW2 |
| Synonyms | |
| Frizzled-4, Fz-4, hFz4, FzE4, CD344, FZD4. | |
| Introduction | |
| Frizzled-4, also known as FZD4 is a 7 transmembrane glycoprotein which belongs to the Frizzled family within the G-protein coupled receptor superfamily. FZD4 acts as a positive regulator of the Wingless type MMTV integration site signaling pathway. These pathways appear to include interactions with G-proteins. FZD4 is implicated in transduction as well as intercellular transmission of polarity information in the course of tissue morphogenesis and differentiated tissues. | |
| Source | |
| Sf9, Baculovirus cells. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| FZD4 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| ADP FGDEEER RCDPIRISMC QNLGYNVTKM PNLVGHELQT DAELQLTTFT PLIQYGCSSQ LQFFLCSVYV PMCTEKINIP IGPCGGMCLS VKRRCEPVLK EFGFAWPESL NCSKFPPQND HNHMCMEGPG DEEVPLPHKT PIQPGEECHS VGTNSDQYIW VKRSLNCVLK CGYDAGLYSR SAKEFTDIW L EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GKHHHHHH | |
| Precautions | |
| FZD10 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9ULW2 ) | |
Background |
Frizzled-10 (FZD10) is a member of the Frizzled family of G protein-coupled receptors (GPCRs) that play critical roles in the Wnt signaling pathway, which is essential for various developmental processes, cell proliferation, and differentiation. Recombinant human FZD10 (rhFZD10) has been developed to facilitate research into its biological functions and potential therapeutic applications, particularly in the context of cancer and regenerative medicine. This paper provides a comprehensive overview of the scientific research on recombinant human FZD10, focusing on its biological functionality, detailed description, and physical properties. Recombinant human FZD10 is primarily used to investigate the role of FZD10 in Wnt signaling and its implications in health and disease. |
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