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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0910-5 | 7 days | 5 µg | $120.00 |
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| RCP0910-20 | 7 days | 20 µg | $290.00 | |||
| RCP0910-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | GID8 Human |
|---|---|
| Description | |
| GID Complex Subunit 8 Human Recombinant | |
| Accession (Primary) | Q9NWU2 |
| Synonyms | |
| GTPase IMAP family member 5, Immunity-associated nucleotide 4-like 1 protein, Immunity-associated nucleotide 5 protein, IAN-5, hIAN5, Immunity-associated protein 3, GIMAP5, IAN4L1, IAN5, IMAP3, HIMAP3, IAN4, IROD. | |
| Introduction | |
| GTPase, IMAP Family Member 5 (GIMAP5) is a part of the GTP-binding superfamily and the immuno-associated nucleotide subfamily of nucleotide-binding proteins. GIMAP5 is an antiapoptotic protein which is required for mitochondrial integrity and T-cell survival. Polymorphisms in GIMAP5 are related with systemic lupus erythematosus. Read-through transcription can be found between GIMAP5 and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene. GIMAP5 also contributes to T-cell quiescence. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The GIMAP5 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 40% glycerol and 2mM DTT. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 85.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS MGGFQRG KYGTMAEGRS EDNLSATPPA LRIILVGKTG CGKSATGNSI LGQPVFESKL RAQSVTRTCQ VKTGTWNGRK VLVVDTPSIF ESQADTQELY KNIGDCYLLS APGPHVLLLV IQLGRFTAQD TVAIRKVKEV FGTGAMRHVV ILFTHKEDLG GQALDDYVAN TDNCSLKDLV RECERRYCAF NNWGSVEEQR QQQAELLAVI ERLGREREGS FHSNDLFLDA QLLQRTGAGA CQEDYRQYQA KVEWQVEKHK QELRENESNW AYKALLRVKH LMLLHYE. | |
| Precautions | |
| GID8 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9NWU2 ) | |
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ADMEbio Team
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ADMEbio Team
