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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0927-2 | 7 days | 2 µg | $120.00 |
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| RCP0927-10 | 7 days | 10 µg | $290.00 | |||
| RCP0927-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | GLTP Human |
|---|---|
| Description | |
| Glycolipid Transfer Protein Human Recombinant | |
| Accession (Primary) | Q9NZD2 |
| Synonyms | |
| Ceramide-1-Phosphate Transfer Protein, Glycolipid Transfer Protein Domain-Containing Protein 1, Glycolipid Transfer Protein Domain Containing 1, GLTP Domain-Containing Protein 1, GLTPD1, GLTPD1, Ceramide-1-phosphate transfer protein, CPTP. | |
| Introduction | |
| Glycolipid Transfer Protein Domain Containing 1 (GLTPD1) belongs to the GLTP family. GLTPD1 mediates the intracellular transfer of ceramide-1-phosphate between organelle membranes and the cell membrane. GLTPD1 is essential for normal structure of the Golgi stacks. In addition, GLTPD1 is able to bind phosphoceramides with a diversity of aliphatic chains, however GLTPD1 has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains. Moreover, GLTPD1 is inefficient with phosphoceramides which contains lignoceryl (C24:0). GLTPD1 participates in the regulation of the cellular levels of ceramide-1-phosphate, and in that way contributes to the regulation of phospholipase PLA2G4A activity and the release of arachidonic acid. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| GLTPD1 protein solution (0.25mg/ml) containing Phosphate buffered saline (pH7.4), 50% glycerol and 1mM DTT. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS MDDSETG FNLKVVLVSF KQCLDEKEEV LLDPYIASWK GLVRFLNSLG TIFSFISKDV VSKLRIMERL RGGPQSEHYR SLQAMVAHEL SNRLVDLERR SHHPESGCRT VLRLHRALHW LQLFLEGLRT SPEDARTSAL CADSYNASLA AYHPWVVRRA VTVAFCTLPT REVFLEAMNV GPPEQAVQML GEALPFIQRV YNVSQKLYAE HSLLDLP. | |
| Precautions | |
| GLTP Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9NZD2 ) | |
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ADMEbio Team
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