Hello, Sign in
My Account
My Account
New customer? Start here
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0940-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
|
||
| RCP0940-10 | 7 days | 10 µg | $290.00 | |||
| RCP0940-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | GNB2L1 Human |
|---|---|
| Description | |
| Guanine Nucleotide Binding Protein beta polypeptide 2-like 1 Human Recombinant | |
| Accession (Primary) | P63244 |
| Synonyms | |
| Transducin Beta Chain 3, G Protein, Beta-3 Subunit, GTP-Binding Regulatory Protein Beta-3 Chain, Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Beta Subunit 3, Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Subunit Beta-3, Hypertension Associated Protein, Guanine Nucleotide Binding Protein (G Protein), Beta Polypeptide 3, GNB3. | |
| Introduction | |
| GNB3 belongs to the WD repeat G protein beta family. GNB3 is an important regulator of alpha subunit, as well as of certain signal transduction receptor and effector. A single-nucleotide polymorphism (C825T) in GNB3 is linked with essential hypertension and obesity. In addition, this polymorphism is also linked with the occurrence of the splice variant GNB3-s, which seems to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Further splice variants may exist for GNB3, however they have not been fully described. Among the diseases associated with GNB3 are syncope, and aortic coarctation. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| GNB3 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.4M Urea. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 80.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS MGEMEQL RQEAEQLKKQ IADARKACAD VTLAELVSGL EVVGRVQMRT RRTLRGHLAK IYAMHWATDS KLLVSASQDG KLIVWDSYTT NKVHAIPLRS SWVMTCAYAP SGNFVACGGL DNMCSIYNLK SREGNVKVSR ELSAHTGYLS CCRFLDDNNI VTSSGDTTCA LWDIETGQQK TVFVGHTGDC MSLAVSPDFN LFISGACDAS AKLWDVREGT CRQTFTGHES DINAICFFPN GEAICTGSDD ASCRLFDLRA DQELICFSHE SIICGITSVA FSLSGRLLFA GYDDFNCNVW DSMKSERVGI LSGHDNRVSC LGVTADGMAV ATGSWDSFLK IWN. | |
| Precautions | |
| GNB2L1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P63244 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
