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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0955-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP0955-20 | 7 days | 20 µg | $290.00 | |||
| RCP0955-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | GP9 Human |
|---|---|
| Description | |
| Glycoprotein-9 Human Recombinant | |
| Accession (Primary) | P14770 |
| Synonyms | |
| Glycogen phosphorylase brain form, EC 2.4.1.1, GPBB, MGC9213, PYGB. | |
| Introduction | |
| Glycogen phosphorylase is one of the phosphorylaseenzymes(EC2.4.1.1). It breaks up glycogeninto glucosesubunits. Glycogenis left with one less glucosemolecule, and the free glucosemolecule is in the form of glucose-1-phosphate. In order to be used for metabolism, it must be converted to glucose-6-phosphateby the enzyme phosphoglucomutase. Glycogen phosphorylase can only act on linearchainsof glycogen(a 1-4 glycosidic linkage). Its work will immediately come to a halt four residues away from a 1-6 branch(which are exceedingly common in glycogen). In these situations, a debranching enzymeis necessary, which will straighten out the chain in that area. Additionally, an alpha 1-6 glucosidaseenzymeis required to break the remaining 1-6 residue that remains in the new linear chain. After all this is done, glycogen phosphorylase can continue. An insulinstimulated enzyme known as phosphoprotein phosphatase(PP-1) inactivates glycogen phosphorylase to prevent glycogen break up. GPBB - a sensitive marker for the AMI diagnosis within 4 hours after the onset of chest pain. It has also been shown that GPBB is increased in a considerable proportion of AMI patients within 2-3 hours from chest pain onset. GPBB is increased early in patients with unstable angina. GPBB can also be a sensitive marker for the detection of peri-operative myocardial ischaemia and infarction in patients undergoing coronary artery bypass grafting. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colourless liquid formualtion. | |
| Formulation | |
| Each mg of protein contains 50% glycerol. | |
| Stability | |
| GPBB although stable at 10°C for 7 days, should be stored below -18°C. Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 85.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Applications | |
| Immunoassays and western blot. | |
| Precautions | |
| GP9 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P14770 ) | |
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ADMEbio Team
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