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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1025-5 | 7 days | 5 µg | $120.00 |
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| RCP1025-20 | 7 days | 20 µg | $290.00 | |||
| RCP1025-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | HLA-DOB Human |
|---|---|
| Description | |
| Major Histocompatibility Complex Class II DO Beta Human Recombinant | |
| Accession (Primary) | P13765 |
| Synonyms | |
| Major Histocompatibility Complex, Class II, DR Alpha, HLA-DRA1, MHC Class II AntigenDRA, MLRW, Histocompatibility AntigenHLA-DR Alpha, HLAClass II Histocompatibility Antigen, DR Alpha Chain, MHC Cell Surface Glycoprotein, HLA-DRA1. | |
| Introduction | |
| Major histocompatibility complex, class II, DR alpha (HLA-DRA) belongs to the MHC class II family. HLA-DRA binds peptides derived from antigens which access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for identification by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mainly by degradation of proteins which access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| HLA-DRA protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH M IKEEHVIIQ AEFYLNPDQS GEFMFDFDGD EIFHVDMAKK ETVWRLEEFG RFASFEAQGA LANIAVDKAN LEIMTKRSNY TPITNVPPEV TVLTNSPVEL REPNVLICFI DKFTPPVVNV TWLRNGKPVT TGVSETVFLP REDHLFRKFH YLPFLPSTED VYDCRVEHWG LDEPLLKHWE FDAPSPLPET TE | |
| Precautions | |
| HLA-DOB Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P13765 ) | |
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ADMEbio Team
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ADMEbio Team
