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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1029-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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| RCP1029-10 | 7 days | 10 µg | $290.00 | |||
| RCP1029-100 | 7 days | 100 µg | $1,920.00 |
Product Overview | |
| Name | HLA-F Human |
|---|---|
| Description | |
| Major Histocompatibility Complex Class I F Human Recombinant | |
| Accession (Primary) | P30511 |
| Synonyms | |
| Major Histocompatibility Complex, Class I, G, HLA-G Histocompatibility Antigen, Class I, G, MHC Class I Antigen G, B2 Microglobulin, HLA G Antigen, HLA Class I Histocompatibility Antigen, Alpha Chain G, Mutant MHC Class Ib Antigen, Mutant MHC Class I Antigen, MHC Class Ib Antigen, HLA-6.0, MHC-G, HLAG, HLA class I histocompatibility antigen, alpha chain G, HLA G antigen, MHC class I antigen G. | |
| Introduction | |
| HLA-G (Major Histocompatibility Complex Class I G) is a member of the HLA class I heavy chain paralogues. This class I molecule is a heterodimer which comprises a heavy chain as well as a light chain, beta-2 microglobulin, while the heavy chain is fixed in the membrane. HLA-G is expressed on fetal derived placental cells. HLA-G is a non-classical class-I HLA molecule linked with immuno-modulatory & anti-inflammatory properties which interacts with inhibitory receptors such as, ILT2/ILT4/KIR2DL4, that are present on different immune cells. HLA-G inhibits the proliferation of T cells, B cells & natural killer cells, moreover it also induces regulatory T cells. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| HLA-G protein solution (0.25mg/ml) contains 20% glycerol and PBS (pH 7.4). | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGSHM GSHSM RYFSAAVSRP GRGEPRFIAM GYVDDTQFVR FDSDSACPRM EPRAPWVEQE GPEYWEEETR NTKAHAQTDR MNLQTLRGYY NQSEASSHTL QWMIGCDLGS DGRLLRGYEQ YAYDGKDYLA LNEDLRSWTA ADTAAQISKR KCEAANVAEQ RRAYLEGTCV EWLHRYLENG KEMLQRADPP KTHVTHHPVF DYEATLRCWA LGFYPAEIIL TWQRDGEDQT QDVELVETRP AGDGTFQKWA AVVVPSGEEQ RYTCHVQHEG LPEPLMLRWK QSSLPTIPI. | |
| Precautions | |
| HLA-F Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P30511 ) | |
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ADMEbio Team
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