| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1034-5 | 7 days | 5 µg | $120.00 |
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| RCP1034-20 | 7 days | 20 µg | $290.00 | |||
| RCP1034-1 | 7 days | 1 mg | $5,760.00 |
Product Overview | |
| Name | HMGB1 Human, Sf9 |
|---|---|
| Description | |
| High-Mobility Group Box 1 Human Recombinant, Sf9 | |
| Accession (Primary) | P09429 |
| Synonyms | |
| High mobility group (nonhistone chromosomal) protein B2, h mobility group box 2, HMG2. | |
| Introduction | |
| HMGB2 belongs to the non-histone chromosomal high-mobility group protein family which are chromatin-associated and highly spread in the nucleus of higher eukaryotic cells. HMGB2 can successfully bend DNA and form DNA circles which indicates that HMGB2 facilitates cooperative interactions between cis-acting proteins by promoting DNA flexibility. Additionally, HMGB2 takes part in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. | |
| Source | |
| Baculovirus. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The HMGB2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 0.1M NaCl and 30% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH TGS MGKGDPN KPRGKMSSYA FFVQTCREEH KKKHPDSSVN FAEFSKKCSE RWKTMSAKEK SKFEDMAKSD KARYDREMKN YVPPKGDKKG KKKDPNAPKR PPSAFFLFCS EHRPKIKSEH PGLSIGDTAK KLGEMWSEQS AKDKQPYEQK AAKLKEKYEK DIAAYRAKGK SEAGKKGPGR PTGSKKKNEP EDEEEEEEEE DEDEEEEDED EE. | |
| Precautions | |
| HMGB1 Human, Sf9 is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P09429 ) | |
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