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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1047-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP1047-20 | 7 days | 20 µg | $290.00 | |||
| RCP1047-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | HOMER3 Human |
|---|---|
| Description | |
| Homer Homolog-3 Human Recombinant | |
| Accession (Primary) | Q9NSC5 |
| Synonyms | |
| Homeodomain-only protein, Lung cancer-associated Y protein, Not expressed in choriocarcinoma protein 1, Odd homeobox protein 1, HOPX, HOD, HOP, LAGY, NECC1, OB1, TOTO, CAMEO, SMAP31. | |
| Introduction | |
| Homeodomain-only protein (HOPX) functions via its interaction with SRF, thus modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. HOPX inhibits SRF-dependent transcription either by hindering SRF binding to DNA or by engaging histone deacetylase (HDAC) proteins which prevent transcription by SRF. HOPX is a homeodomain protein which lacks certain conserved residues required for DNA binding. HOPX overexpression causes cardiac hypertrophy. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| HOPX protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0) and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGSH MSAETA SGPTEDQVEI LEYNFNKVDK HPDSTTLCLI AAEAGLSEEE TQKWFKQRLA KWRRSEGLPS ECRSVTD. | |
| Precautions | |
| HOMER3 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9NSC5 ) | |
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ADMEbio Team
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ADMEbio Team
