Hello, Sign in
My Account
My Account
New customer? Start here
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1109-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
|
||
| RCP1109-10 | 7 days | 10 µg | $290.00 | |||
| RCP1109-100 | 7 days | 100 µg | $1,920.00 |
Product Overview | |
| Name | IER3 Human |
|---|---|
| Description | |
| Immediate Early Response 3 Human Recombinant | |
| Accession (Primary) | P46695 |
| Synonyms | |
| Gastric intrinsic factor, Intrinsic factor, INF, IF, GIF, IFMH, TCN3, Cobalamin/Vitamin B-12 binding transport protein. | |
| Introduction | |
| Intrinsic Factor is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12 in the terminal ileum. Vitamin B12 is essential for erythrocyte maturation and mutations in the Intrinsic Factor may lead to congenital pernicious anemia. Upon entry into the stomach, vitamin B12 binds to one of two B12 binding proteins present in the gastric fluid. In the less acidic environment of the small intestine, these proteins dissociate from the vitamin, allowing it to bind to intrinsic factor and enter the portal circulation through a receptor in the ileal mucosa specific for the B12-intrinsic factor complex. | |
| Source | |
| Sf9 Insect Cells. | |
| Physical Appearance | |
| Sterile Filtered pink solution. | |
| Formulation | |
| The protein solution contains 20mM HEPES pH-8.0, 100mM NaCl and 20% Glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Precautions | |
| IER3 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P46695 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
