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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1131-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP1131-20 | 7 days | 20 µg | $290.00 | |||
| RCP1131-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | IRGM Human |
|---|---|
| Description | |
| Immunity-Related GTPase Family, M Human Recombinant | |
| Accession (Primary) | A1A4Y4 |
| Synonyms | |
| Iron-sulfur cluster assembly enzyme ISCU mitochondrial, NifU-like N-terminal domain-containing protein, NifU-like protein, ISCU, NIFUN, HML, ISU2, NIFU, hnifU, MGC74517, 2310020H20Rik. | |
| Introduction | |
| Iron-sulfur cluster assembly enzyme (ISCU) belongs to the nifU family. Iron-sulfur (Fe-S) clusters are required for several mitochondrial enzymes and other subcellular compartment proteins. ISCU interacts with ISCS (a cysteine desulfurase) to sequester inorganic sulfur for Fe-S cluster assembly. The ISCU-ISCS protein complex localizes in both mitochondria and cytosol, implying that Fe-S cluster assembly occurs in multiple subcellular compartments in mammalian cells. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The ISCU solution (0.5 mg/ml) 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 2mM DTT and 100mM NaCl. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH M YHKKVVDHY ENPRNVGSLD KTSKNVGTGL VGAPACGDVM KLQIQVDEKG KIVDARFKTF GCGSAIASSS LATEWVKGKT VEEALTIKNT DIAKELCLPP VKLHCSMLAE DAIKAALADY KLKQEPKKGE AEKK. | |
| Precautions | |
| IRGM Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( A1A4Y4 ) | |
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ADMEbio Team
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ADMEbio Team
