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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1141-2 | 7 days | 2 µg | $120.00 |
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| RCP1141-10 | 7 days | 10 µg | $290.00 | |||
| RCP1141-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | JAM2 Human, Sf9 |
|---|---|
| Description | |
| Junctional Adhesion Molecule 2 Human Recombinant, Sf9 | |
| Accession (Primary) | P57087 |
| Synonyms | |
| Junctional Adhesion Molecule 3, Junctional Adhesion Molecule C, JAM-C, JAM-2, JAM-3. | |
| Introduction | |
| JAM3 belongs to the junctional adhesion molecule protein family and functions as a receptor for another member of this family. JAM3 plays a part in cell-cell adhesion. The soluble form of JAM3 is a mediator of angiogenesis. JAM3 is a counter-receptor for ITGAM, mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN). A mutation in an intron of the JAM3 gene is linked with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. | |
| Source | |
| E.coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The JAM3 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 2mM EDTA, 5mM DTT and 50% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGSM VNLKSS NRTPVVQEFE SVELSCIITD SQTSDPRIEW KKIQDEQTTY VFFDNKIQGD LAGRAEILGK TSLKIWNVTR RDSALYRCEV VARNDRKEID EIVIELTVQV KPVTPVCRVP KAVPVGKMAT LHCQESEGHP RPHYSWYRND VPLPTDSRAN PRFRNSSFHL NSETGTLVFT AVHKDDSGQY YCIASNDAGS ARCEEQEMEV YDLN | |
| Precautions | |
| JAM2 Human, Sf9 is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P57087 ) | |
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ADMEbio Team
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ADMEbio Team
