| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1143-5 | 7 days | 5 µg | $120.00 |
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| RCP1143-20 | 7 days | 20 µg | $290.00 | |||
| RCP1143-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | JAZF1 Human |
|---|---|
| Description | |
| JAZF zinc finger 1 Human Recombinant | |
| Accession (Primary) | Q86VZ6 |
| Synonyms | |
| Jun dimerization protein 2, JDP2, JUNDM2, Progesterone Receptor Co-Activator. | |
| Introduction | |
| Jun dimerization protein 2 (JDP2) is a component of the AP-1 transcription factor which inhibits transactivation mediated by the Jun family of proteins. JDP2 is involved in various transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. In addition, JDP2 can act as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. JDP2 controls transcription via direct regulation of the modification of histones and the assembly of chromatin. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| JDP2 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol, 1mM DTT, 1mM EDTA and 250mM imidazole. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGSH MMPGQI PDPSVTTGSL PGLGPLTGLP SSALTVEELK YADIRNLGAM IAPLHFLEVK LGKRPQPVKS ELDEEEERRK RRREKNKVAA ARCRNKKKER TEFLQRESER LELMNAELKT QIEELKQERQ QLILMLNRHR PTCIVRTDSV KTPESEGNPL LEQLEKK. | |
| Precautions | |
| JAZF1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q86VZ6 ) | |
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