| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1154-5 | 7 days | 5 µg | $120.00 |
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| RCP1154-20 | 7 days | 20 µg | $290.00 | |||
| RCP1154-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | KCTD15 Human |
|---|---|
| Description | |
| Potassium Channel Tetramerisation Domain Containing 15 Human Recombinant | |
| Accession (Primary) | Q96SI1 |
| Immunogen | |
| Anti-human KCTD15 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human KCTD15 protein 1-159 amino acids purified from E. coli. | |
| Synonyms | |
| BTB/POZ domain-containing protein KCTD15, Potassium channel tetramerisation domain containing 15, KCTD15, MGC2628, MGC25497. | |
| Introduction | |
| KCTD15 protein is encoded in humans by the KCTD15 gene. KCTD15 is expressed at a high level in the brain and the hypothalamus. The potassium channel KCTD15 was identified as a genetic loci linked to higher than normal BMI in humans along with genes such as GNPDA2, MTCH2, FTO, and TMEM18. SNPs (Single nucleotide polymorphisms) in non-diabetic and diabetic patients showed that FTO was most strongly associated with obesity while MTCH2 and GNPDA2 were still notably associated with higher than normal BMI levels. | |
| Formulation | |
| 1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide. | |
| Applications | |
| KCTD15 antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| PAT2B11AT. | |
| Ig Subclass | |
| Mouse IgG 2b heavy chain and k light chain. | |
| Purification Method | |
| KCTD15 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. | |
| Storage Procedures | |
| For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
| Stability / Shelf Life | |
| Life 12 months at -20°C. 1 month at 4°C. | |
| Precautions | |
| KCTD15 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q96SI1 ) | |
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ADMEbio Team
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ADMEbio Team