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KRT5 Human

Cytokeratin 5 Human Recombinant

 
Catalog #
RCP1201
Uniprot Id
P13647
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
RCP1201-5 7 days 5 µg $120.00
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RCP1201-20 7 days 20 µg $290.00
RCP1201-1 7 days 1 mg $4,320.00
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Product Overview

NameKRT5 Human
Description
Cytokeratin 5 Human Recombinant
Accession (Primary)P13647
Immunogen
Anti-human KRT8 mAb, clone PAT3D11A, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human KRT8 protein purified from E. coli.
Synonyms
Keratin type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, KRT8, CYK8, KO, CK8, K2C8, CARD2.
Introduction
Cytokeratin 8 (KRT8) belongs to the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. KRT8 has a role in retaining cellular structural integrity and also functions in signal transduction and cellular differentiation. KRT8 gene mutations cause cryptogenic cirrhosis.
Physical Appearance
Sterile filtered colorless solution.
Formulation
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Applications
The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.
Type
Mouse Anti Human Monoclonal.
Clone
PAT3D11A.
Ig Subclass
Mouse IgG 3 heavy chain and Kappa light chain.
Storage Procedures
For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
Stability / Shelf Life
12 months at -20°C. 1 month at 4°C.
Precautions
KRT5 Human is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( P13647 )

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