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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1202-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP1202-20 | 7 days | 20 µg | $290.00 | |||
| RCP1202-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | KRT8 Human |
|---|---|
| Description | |
| Cytokeratin 8 Human Recombinant | |
| Accession (Primary) | P05787 |
| Synonyms | |
| Keratin type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, KRT8, CYK8, KO, CK8, K2C8, CARD2. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Each mg was lyophilized with 1xPBS, 0.4% SDS and 4mM DTT. | |
| Stability | |
| Store lyophilized KRT8 at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| GGLSSAYGGL TSPGLSYSLG SSFGSGAGSS SFSRTSSSRA VVVKKIETRD GKLVSESSDV LPK | |
| Solubility | |
| It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it on cell culture. | |
| Background | |
| Cytokeratin 8, also known as KRT8, is a part of the type II keratin family clustered on the long arm of chromosome 12 which plays an important role in the structural integrity of epithelial cells. KRT8 pairs with keratin 18 (a type I keratin) to form heterodimers, which assemble into intermediate filaments. KRT8 takes part in retaining cellular structural integrity and also participates in signal transduction and cellular differentiation. | |
| Precautions | |
| KRT8 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P05787 ) | |
References |
1. Title :Role for the PP2A/B56 Phosphatase in Regulating 14-3-3 Release from Cdc25 to Control Mitosis. Publication :Copyright 2006 Elsevier Inc. All rights reserved.Cell, Volume 127, Issue 4 , 759-773, 17 November 2006 doi:10.1016/j.cell.2006.10.035 Link : KRT8 prospec publication 2. Title :Role for the PP2A/B56? Phosphatase in Regulating 14-3-3 Release from Cdc25 to Control Mitosis. Publication : Received 3 May 2006. Revised 23 August 2006. Accepted 9 October 2006. Available online 16 November 2006. Published: November 16, 2006. Link : Cytokeratin 8 prospec publication |
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