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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1231-1 | 7 days | 1 µg | $120.00 |
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| RCP1231-5 | 7 days | 5 µg | $290.00 | |||
| RCP1231-50 | 7 days | 50 µg | $1,920.00 |
Product Overview | |
| Name | LCP2 Human |
|---|---|
| Description | |
| Lymphocyte Cytosolic Protein 2 Human Recombinant | |
| Accession (Primary) | Q13094 |
| Immunogen | |
| Anti-human LDHA mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human LDHA amino acids 1-332 purified from E. coli. | |
| Synonyms | |
| LDH-A, GSD11, LDH1, LDHM, PIG19, EC 1.1.1.27, lactate dehydrogenase M, LDH-M, LDH-1, L-lactate dehydrogenase A chain, LDH muscle subunit, Renal carcinoma antigen NY-REN-59, Cell proliferation-inducing gene 19 protein, LDHA. | |
| Introduction | |
| LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA is localized primarily in muscle tissue and is part of the lactate dehydrogenase family. Mutations in LDHA have been linked to exertional myoglobinuria. LDH1 is decreased in essential thrombocythemia. LDHA is induced through a non-genomic pathway of estrogen action. Reduction in LDH-A activity results in stimulation of mitochondrial respiration and decrease of mitochondrial membrane potential. | |
| Formulation | |
| 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. | |
| Applications | |
| LDHA antibody has been tested by ELISA, Western blot and Immunofluorescence analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis and Immunofluorescence is 1:500 ~ 8,000. Recommended starting dilution is 1:1,000. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| PAT1A4AT. | |
| Ig Subclass | |
| Mouse IgG2b heavy chain and κ light chain. | |
| Purification Method | |
| LDHA antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. | |
| Storage Procedures | |
| For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
| Stability / Shelf Life | |
| 12 months at -20°C. 1 month at 4°C. | |
| Precautions | |
| LCP2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q13094 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
