Hello, Sign in
My Account
My Account
New customer? Start here
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1251-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
|
||
| RCP1251-20 | 7 days | 20 µg | $290.00 | |||
| RCP1251-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | LITAF Human |
|---|---|
| Description | |
| Lipopolysaccharide-Induced TNF Factor Human Recombinant | |
| Accession (Primary) | Q99732 |
| Synonyms | |
| C-X-C motif chemokine 5, Small-inducible cytokine B5, Cytokine LIX, Cxcl5, Scyb5, LIX, GCP-2, Scyb6, ENA-78, AMCF-II. | |
| Introduction | |
| Chemokine (C-X-C motif) ligand 5 (CXCL5) is a small cytokine belonging to the CXC chemokine family that is also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78). It is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. Expression of CXCL5 has also been observed in eosinophils, and can be inhibited with the type II IFN. This chemokine stimulates the chemotaxis of neutrophils possesses angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2. The gene for CXCL5 is encoded on four exons and is located on human chromosome 4 amongst several other CXC chemokine genes. CXCL5 has been implicated in connective tissue remodelling. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| LIX Mouse is lyophilized from a 0.2 µm filtered solution in PBS. | |
| Stability | |
| Lyophilized LIX Mouse although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL5 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| VIAA TELRCV CLTVTPKINP KLIANLEVIP AGPQCPTVEV IAKLKNQKEV CLDPEAPVIK KIIQKILGSD KKKA. | |
| Biological Activity | |
| The ED 50 , as measured by its ability to chemoattract human CXCR2-transfected mouse BaF3 cells, is less than 0.1 µg/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized LIX Mouse in sterile 18M-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| LITAF Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q99732 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
