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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1283-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP1283-20 | 7 days | 20 µg | $290.00 | |||
| RCP1283-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | LY6D Human |
|---|---|
| Description | |
| Lymphocyte Antigen 6 Complex, Locus D Human Recombinant | |
| Accession (Primary) | Q14210 |
| Immunogen | |
| Ly-6G-transfected cell line. | |
| Synonyms | |
| Lymphocyte antigen 6G, Ly-6G, Ly-6G.1, Ly6g, Gr1, Gr-1. | |
| Introduction | |
| Myeloid differentiation antigen Gr1 (Ly6G) is a GPI-anchored protein, which is briefly expressed on monocytes in the bone marrow. The level of the Ly6G expression in the bone marrow completely correlates with granulocyte differentiation and maturation. Ly6G ligation on murine neutrophils inhibits neutrophil recruitment, thus providing the first evidence of a function for the Ly6G molecule. Ly6G is seen primarily on neutrophils, also in a subgroup of eosinophils, differentiating pre-monocytes and plasmacytoid dendritic cells. | |
| Formulation | |
| 1mg/ml in PBS (after reconstitution). | |
| Solubility | |
| Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. | |
| Applications | |
| Flow cytometry, immunohistochemistry, cell depletion. This antibody recognizes only Ly-6G which is expressed on most myeloid cells in the bone marrow and all peripheral granulocytes. For flow cytometry, use 10 µl/10 6 cells. Exact titer for cell depletion in vivo (cytotoxicity) should be determined by the investigator. | |
| Type | |
| Rat Anti Mouse Monoclonal. | |
| Clone | |
| YRmLy-6G. | |
| Ig Subclass | |
| Rat IgG2a. | |
| Purification Method | |
| Protein A column. | |
| Storage Procedures | |
| In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. | |
| Available Conjugates | |
| This antibody is also available conjugated to biotin and FITC. | |
| Shipping Conditions | |
| Antibody is shipped lyophilized at ambient temperature. | |
| Precautions | |
| LY6D Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q14210 ) | |
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ADMEbio Team
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ADMEbio Team
