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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1312-50 | 7 days | 50 µg | $1,200.00 |
Select product before adding to cart
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| RCP1312-100 | 7 days | 100 µg | $1,800.00 | |||
| RCP1312-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | MALD3 |
|---|---|
| Description | |
| Non-Specific Lipid-Transfer Protein Mal d 3 Recombinant | |
| Accession (Primary) | Q9M5X7 |
| Synonyms | |
| Mesencephalic astrocyte-derived neurotrophic factor, Protein ARMET, ARP, arginine-rich mutated in early stage tumors, Arginine-rich protein. | |
| Introduction | |
| MANF is a 20kDa protein which belongs to the ARMET family. MANF was originally known as an arginine-rich region protein which was extremely mutated in a large number of tumors. MANF Expression is induced during ER stress, signifying that MANF takes part in protein quality control during ER stress. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Filtered (0.2 µm) and lyophilized from a concentrated (1mg/ml) solution in 1×PBS, pH7.4. | |
| Stability | |
| Lyophilized MANF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution MANF should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| LRPGDCEVCI SYLGRFYQDL KDRDVTFSPA TIENELIKFC REARGKENRL CYYIGATDDA ATKIINEVSK PLAHHIPVEK ICEKLKKKDS QICELKYDKQ IDLSTVDLKK LRVKELKKIL DDWGETCKGC AEKSDYIRKI NELMPKYAPK AASARTDL. | |
| Biological Activity | |
| The ED50 was determined by its ability to stimulate the proliferation of rat C6 cells is typically 15-25 µg/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized MANF in sterile 18M-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| MALD3 is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9M5X7 ) | |
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