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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1321-5 | 7 days | 5 µg | $120.00 |
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| RCP1321-20 | 7 days | 20 µg | $290.00 | |||
| RCP1321-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | MAPRE3 Human |
|---|---|
| Description | |
| Microtubule-Associated Protein, RP/EB Family, Member 3 Human Recombinant | |
| Accession (Primary) | Q9UPY8 |
| Synonyms | |
| TAU, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND. | |
| Introduction | |
| MAPT is a neuronal microtubule associated protein localized mostly on axons. MAPT promotes tubulin polymerisation and stabilizes microtubules, however it also serves to connect certain signalling pathways to the cytoskeleton. MAPT, in its hyperphosphorylated form, is the main part of paired helical filaments (PHF) and neurofibrillary lesions in Alzheimer''s disease (AD) brain. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| The MAPT solution (0.5mg/ml) contains 20mM Tris-HCl pH-8, 1mM DTT, 0.2M NaCl & 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 85.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MAEPRQEFEV MEDHAGTYGL GDRKDQGGYT MHQDQEGDTD AGLKAEEAGI GDTPSLEDEA AGHVTQARMV SKSKDGTGSD DKKAKGADGK TKIATPRGAA PPGQKGQANA TRIPAKTPPA PKTPPSSGEP PKSGDRSGYS SPGSPGTPGS RSRTPSLPTP PTREPKKVAV VRTPPKSPSS AKSRLQTAPV PMPDLKNVKS KIGSTENLKH QPGGGKVQIV YKPVDLSKVT SKCGSLGNIH HKPGGGQVEV KSEKLDFKDR VQSKIGSLDN ITHVPGGGNK KIETHKLTFR ENAKAKTDHG AEIVYKSPVV SGDTSPRHLS NVSSTGSIDM VDSPQLATLA DEVSASLAKQ GL. | |
| Precautions | |
| MAPRE3 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9UPY8 ) | |
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ADMEbio Team
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