| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1370-5 | 7 days | 5 µg | $120.00 |
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| RCP1370-20 | 7 days | 20 µg | $290.00 | |||
| RCP1370-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | MIS12 Human |
|---|---|
| Description | |
| MIS12 Human Recombinant | |
| Accession (Primary) | Q9H081 |
| Synonyms | |
| MART-1, MART1, Melanoma antigen recognized by T-cells 1, Antigen LB39-AA, Antigen SK29-AA, Protein Melan-A, MLANA. | |
| Introduction | |
| Melan-A (MLANA), is engaged in melanosome biogenesis by ensuring the stability of GPR143. MLANA takes part in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is essential to the formation of stage II melanosomes. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| The MLANA solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 85% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS CRRRNGY RALMDKSLHV GTQCALTRRC PQEGFDHRDS KVSLQEKNCE PVVPNAPPAY EKLSAEQSPP PYSP. | |
| References | |
| Title: Human heat shock protein 70 enhances tumor antigen presentation through complex formation and intracellular antigen delivery without innate immune signaling Publications: Journal of Biological Chemistry 282.43 (2007): 31688-31702. Link: http://www.jbc.org/content/282/43/31688.full | |
| Precautions | |
| MIS12 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9H081 ) | |
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