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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1383-5 | 7 days | 5 mg | $320.00 |
Select product before adding to cart
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| RCP1383-25 | 7 days | 25 mg | $1,260.00 | |||
| RCP1383-100 | 7 days | 100 mg | $3,016.00 |
Product Overview | |
| Name | MOG |
|---|---|
| Description | |
| Myelin Oligodendrocyte Glycoprotein | |
| Immunogen | |
| synthetic pMOG 35-55. | |
| Synonyms | |
| MGC26137, MOG, MYELIN-OLIGODENDROCYTE GLYCOPROTEIN. | |
| Introduction | |
| MOG is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. MOG is involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified Minor component of the myelin sheath is involved in completion and/or maintenance of the myelin sheath and in cell- cell communication. | |
| Formulation | |
| 1mg/ml in PBS (after reconstitution). | |
| Solubility | |
| Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. | |
| Applications | |
| Direct ELISA, Western Blot, Immuneprecipitation, immunohistochemistry. | |
| Type | |
| Mouse Antibody Monoclonal. | |
| Clone | |
| NYRMOG. | |
| Ig Subclass | |
| mouse IgG1. | |
| Purification Method | |
| Ion exchange column. | |
| Storage Procedures | |
| In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. | |
| Shipping Conditions | |
| Antibody is shipped lyophilized at ambient temperature. | |
| Titer | |
| By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories). | |
| Precautions | |
| MOG is for research use only and not for use in diagnostic or therapeutic procedures. | |
References |
Title: In vivo expansion of T reg cells with IL-2–mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression Publication: The Journal of experimental medicine206.4 (2009): 751-760. Link: MOG prospec publication |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
