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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1414-50 | 7 days | 50 µg | $400.00 |
Select product before adding to cart
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| RCP1414-100 | 7 days | 100 µg | $600.00 | |||
| RCP1414-1 | 7 days | 1 mg | $2,400.00 |
Product Overview | |
| Name | MUC1 ( 47 a.a.) Human |
|---|---|
| Description | |
| Mucin-1 (47 a.a.) Human Recombinant | |
| Accession (Primary) | P15941 |
| Introduction | |
| Human Mucin-1 (CA15-3), aka MUC1, is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. This protein has alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit roles in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Mucins line the apical surface of epithelial cells in the stomach, lungs, intestines, eyes and other tissues. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Overexpression of CA15-3 is often associated with colon, breast, ovarian, lung and pancreatic cancers. | |
| Source | |
| Human carcinoma cell line. | |
| Physical Appearance | |
| Clear to opalescent colorless frozen solution. | |
| Formulation | |
| MUC1 is supplied in a 0.05M sodium phosphate buffer, pH 7.5, 0.09% NaN3 and 0.15M NaCl. | |
| Stability | |
| Human MUC1 although stable at 4°C for 1 week, should be stored at -20°C. | |
| Purity | |
| Greater than 60%. | |
| Human Virus Test | |
| Tissue sample tested and found negative for HIV-1 & 2 antibodies, HBsAg, and Hepatitis-C antibodies, Syphilis and HIV/HBV/HCV NAT. | |
| Precautions | |
| MUC1 ( 47 a.a.) Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P15941 ) | |
Background |
Human Mucin-1 also known as MUC1, is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. MUC1 has alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit roles in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Mucins line the apical surface of epithelial cells in the stomach, lungs, intestines, eyes and other tissues. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Overexpression of MUC1 can be related to various cancers. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
