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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1427-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP1427-20 | 7 days | 20 µg | $290.00 | |||
| RCP1427-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | MYL12A Human |
|---|---|
| Description | |
| Myosin Light Chain 12A Human Recombinant | |
| Accession (Primary) | P19105 |
| Synonyms | |
| Myosin light chain 12B regulatory, Myosin regulatory light chain 2-B smooth muscle isoform, Myosin regulatory light chain 20 kDa, Myosin regulatory light chain MRLC2, MYLC2B, MRLC2, MLC-2A, MLC-B, SHUJUN-1 MLC20. | |
| Introduction | |
| Myosin is composed of 2 nonphosphorylatable alkali light chains, 2 heavy chains and 2 phosphorylatable regulatory light chains. MYL12B is a hexameric ATPase cellular motor protein which controls contraction in smooth muscle and non-muscle cells through phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regulatory light chains catalyzed by MLCK in the presence of calcium and calmodulin, rises Actin-activated myosin ATPase activity, thus regulating contractile activity. | |
| Source | |
| E.coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The MYL12B solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 200mM Nacl, 2mM DTT and 40% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGSH MSSKKA KTKTTKKRPQ RATSNVFAMF DQSQIQEFKE AFNMIDQNRD GFIDKEDLHD MLASLGKNPT DAYLDAMMNE APGPINFTMF LTMFGEKLNG TDPEDVIRNA FACFDEEATG TIQEDYLREL LTTMGDRFTD EEVDELYREA PIDKKGNFNY IEFTRILKHG AKDKDD | |
| Precautions | |
| MYL12A Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P19105 ) | |
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ADMEbio Team
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