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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1450-2 | 7 days | 2 µg | $120.00 |
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| RCP1450-10 | 7 days | 10 µg | $290.00 | |||
| RCP1450-100 | 7 days | 100 µg | $1,920.00 |
Product Overview | |
| Name | NANOGP8 Human |
|---|---|
| Description | |
| Nanog Homeobox Pseudogene 8 Human Recombinant | |
| Accession (Primary) | Q6NSW7 |
| Synonyms | |
| NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog. | |
| Introduction | |
| NANOG is a multidomain homeobox transcription factor which functions to maintain the undifferentiated state of pluripotent stem cells. NANOG expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered solution. | |
| Formulation | |
| NANOG protein solution contains PBS and 50mM Arginine. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE analysis. | |
| Amino acid sequence | |
| VDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDVGGYGRK KRRQRRR | |
| Precautions | |
| NANOGP8 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q6NSW7 ) | |
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ADMEbio Team
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