| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1490-5 | 7 days | 5 µg | $120.00 |
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| RCP1490-20 | 7 days | 20 µg | $290.00 | |||
| RCP1490-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | NFU1 Human |
|---|---|
| Description | |
| NFU1 Human Recombinant | |
| Accession (Primary) | Q9UMS0 |
| Synonyms | |
| NGB. | |
| Introduction | |
| Neuroglobin, 151 amino acid residue protein, mainly expressed in vertebrate brain and retina, is a recently identified member of the globin superfamily. Augmenting O (2) supply, neuroglobin promotes survival of neurons upon hypoxic injury, potentially limiting brain damage. Moreover, neuroglobin may be a novel oxidative stress-responsive sensor for signal transduction in the brain. Neuroglobin expression is increased by neuronal hypoxia in vitro and focal cerebral ischemia in vivo, and neuronal survival after hypoxia is reduced by inhibiting neuroglobin expression with an antisense oligodeoxynucleotide and enhanced by neuroglobin overexpression. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Filtered and lyophilized from 0.5mg/ml in 0.05M phosphate buffer, 0.1M NaCl, pH 7.2. | |
| Stability | |
| Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. | |
| Purity | |
| Greater than 95% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MERPEPELIR QSWRAVSRSP LEHGTVLFAR LFALEPDLLP LFQYNCRQFS SPEDCLSSPE FLDHIRKVML VIDAAVTNVE DLSSLEEYLA SLGRKHRAVG VKLSSFSTVG ESLLYMLEKC LGPAFTPATR AAWSQLYGAV VQAMSRGWDG E. | |
| Solubility | |
| Add H2O and let the lyophilized pellet dissolve completely. | |
| Precautions | |
| NFU1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9UMS0 ) | |
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ADMEbio Team
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