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NFU1 Human

NFU1 Human Recombinant

 
Catalog #
RCP1490
Uniprot Id
Q9UMS0
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
RCP1490-5 7 days 5 µg $120.00
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RCP1490-20 7 days 20 µg $290.00
RCP1490-1 7 days 1 mg $4,320.00
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Product Overview

NameNFU1 Human
Description
NFU1 Human Recombinant
Accession (Primary)Q9UMS0
Synonyms
NGB.
Introduction
Neuroglobin, 151 amino acid residue protein, mainly expressed in vertebrate brain and retina, is a recently identified member of the globin superfamily. Augmenting O (2) supply, neuroglobin promotes survival of neurons upon hypoxic injury, potentially limiting brain damage. Moreover, neuroglobin may be a novel oxidative stress-responsive sensor for signal transduction in the brain. Neuroglobin expression is increased by neuronal hypoxia in vitro and focal cerebral ischemia in vivo, and neuronal survival after hypoxia is reduced by inhibiting neuroglobin expression with an antisense oligodeoxynucleotide and enhanced by neuroglobin overexpression.
Source
Escherichia Coli.
Physical Appearance
Filtered White lyophilized (freeze-dried) powder.
Formulation
Filtered and lyophilized from 0.5mg/ml in 0.05M phosphate buffer, 0.1M NaCl, pH 7.2.
Stability
Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Purity
Greater than 95% as determined by SDS-PAGE.
Amino acid sequence
MERPEPELIR QSWRAVSRSP LEHGTVLFAR LFALEPDLLP LFQYNCRQFS SPEDCLSSPE FLDHIRKVML VIDAAVTNVE DLSSLEEYLA SLGRKHRAVG VKLSSFSTVG ESLLYMLEKC LGPAFTPATR AAWSQLYGAV VQAMSRGWDG E.
Solubility
Add H2O and let the lyophilized pellet dissolve completely.
Precautions
NFU1 Human is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( Q9UMS0 )

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