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NME2 Human

Non-Metastatic Cells 2 Human Recombinant

 
Catalog #
RCP1506
Uniprot Id
P22392
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
RCP1506-5 7 days 5 µg $120.00
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RCP1506-25 7 days 25 µg $290.00
RCP1506-1 7 days 1 mg $3,600.00
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Product Overview

NameNME2 Human
Description
Non-Metastatic Cells 2 Human Recombinant
Accession (Primary)P22392
Synonyms
Nucleoside diphosphate kinase B, NDPK-B, NDPKB, NM23-H2, NM23B.
Introduction
Non-Metastatic Cells 2 or NME2, is a protein, that acts as a nucleoside diphosphate kinase. This protein is of a heterodimeric structure and has 152 aa A & B polypeptide chains that builds the whole protein. Erythrocyte NDP kinase beta subunit has an identical structure to NME2. NDP kinases linked to nucleoside triphosphates synthesis and it appears as though NME2 takes part in regulating signal transduction.
Source
E.coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The NME2 solution (1mg/ml) contains 10% glycerol, 20mM Tris-HCl buffer (pH 8.0) and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MANLERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVAMKF LRASEEHLKQ HYIDLKDRPF FPGLVKYMNS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRNIIHGS DSVKSAEKEI SLWFKPEELV DYKSCAHDWV YE
Biological Activity
Specific activity is > 1,800unit/mg, and is defined as the amount of enzyme that convert 1.0 umole each of ATP and TDP to ADP and TTP per minute at pH 7.5 at 25C in a couple system with PK/LDH.
Precautions
NME2 Human is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( P22392 )

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