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NME3 Human

Non-Metastatic Cells 3 Human Recombinant

 
Catalog #
RCP1508
Uniprot Id
Q13232
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
RCP1508-5 7 days 5 µg $120.00
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RCP1508-20 7 days 20 µg $290.00
RCP1508-1 7 days 1 mg $4,320.00
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Product Overview

NameNME3 Human
Description
Non-Metastatic Cells 3 Human Recombinant
Accession (Primary)Q13232
Synonyms
Nucleoside diphosphate kinase 3, c371H6.2, DR-nm23, KIAA0516, NDPK-C, NDPKC, NM23-H3, NM23H3.
Introduction
Non-Metastatic Cells 3 or NME3 is a possible suppressor of metastasis. NME3 can be found at a lower levels in greatly metastatic cells when compared to cells that has less metastatic potential NME3 is crucial for the nucleoside triphosphates synthesis, also, in apoptosis induction & hematopoiesis. NME3 is can be expressed during early stages of myeloid differentiation of greatly purified CD34+ cells.
Source
E.coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The NME3 solution (0.5mg/ml) contains 50% glycerol, 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl and 2mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH M ERTFLAVKP DGVQRRLVGE IVRRFERKGF KLVALKLVQA SEELLREHYA ELRERPFYGR LVKYMASGPV VAMVWQGLDV VRTSRALIGA TNPADAPPGT IRGDFCIEVG KNLIHGSDSV ESARREIALW FRADELLCWE DSAGHWLYE
Biological Activity
Specific activity is > 150unit/mg, and is defined as the amount of enzyme that convert 1.0 umole each of ATP and TDP to ADP and TTP per minute at pH 7.5 at 25C in a couple system with PK/LDH.
Precautions
NME3 Human is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( Q13232 )

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