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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1523-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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| RCP1523-10 | 7 days | 10 µg | $290.00 | |||
| RCP1523-100 | 7 days | 100 µg | $1,920.00 |
Product Overview | |
| Name | NREP Human |
|---|---|
| Description | |
| Neuronal Regeneration Related Protein Human Recombinant | |
| Accession (Primary) | Q16612 |
| Immunogen | |
| Anti-human NRG1 mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NRG1 amino acids 20-241 purified from E. coli. | |
| Introduction | |
| NRG1 is one of 4 proteins in the neuregulin family which act on the EGFR family of receptors. NRG1 was initially identified as a 44kDa glycoprotein that interacts with the ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. In various brain areas, NRG1 is expressed at synaptic regions and its processing can be regulated by neuronal activity. The HRG-beta3variant of NRG1, along with HRG-alpha, beta1 and beta2 variants, was identified in various normal tissues and cancer cell lines. | |
| Formulation | |
| 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. | |
| Applications | |
| NRG1 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 2,000. Recommended starting dilution is 1:1,000. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| Pk1G13AT. | |
| Ig Subclass | |
| Mouse IgG1 heavy chain and κ light chain. | |
| Purification Method | |
| NRG1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. | |
| Storage Procedures | |
| For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
| Stability / Shelf Life | |
| 12 months at -20°C. 1 month at 4°C. | |
| Precautions | |
| NREP Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q16612 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
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ADMEbio Team
