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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1524-2 | 7 days | 2 µg | $120.00 |
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| RCP1524-10 | 7 days | 10 µg | $290.00 | |||
| RCP1524-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | NRIP3 Human |
|---|---|
| Description | |
| Nuclear Receptor-Interacting Protein 3 Human Recombinant | |
| Accession (Primary) | Q9NQ35 |
| Synonyms | |
| Neuritin 1, NRN1, NRN, dJ380B8.2, Neuritin. | |
| Introduction | |
| Neuritin (NRN1) is a neurotrophic factor, which is expressed in response to induction of neuronal activity by NGF, BDNF, NT3 and other neural stimulators. NRN1 is expressed principally in postmitotic-differentiating neurons of the developing nervous system and in neuronal structures related to synaptic plasticity in the adult nervous system. NRN1 functions as a molecular mediator of neurite outgrowth, neuronal survival, and synaptic maturation. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The NRN1 was lyophilized from a 0.2 µm filtered concentrated solution in 1×PBS, pH 7.4. | |
| Stability | |
| Lyophilized NRN1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution NRN1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| AGKCDAVFKG FSDCLLKLGD SMANYPQGLD DKTNIKTVCT YWEDFHSCTV TALTDCQEGA KDMWDKLRKE SKNLNIQGSL FELCGSGN. | |
| Biological Activity | |
| The ED 50 as determined by a cell proliferation assay using rat C6 cells is less than 25ng/ml, corresponding to a specific activity of > 4.0 × 10 4 IU/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized NRN1 in sterile 18M-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| NRIP3 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9NQ35 ) | |
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ADMEbio Team
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