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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1539-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP1539-20 | 7 days | 20 µg | $290.00 | |||
| RCP1539-1 | 7 days | 1 mg | $6,240.00 |
Product Overview | |
| Name | NUP210 Human |
|---|---|
| Description | |
| Nucleopurin 210kDa Recombinant Human | |
| Accession (Primary) | Q8TEM1 |
| Synonyms | |
| Nuclear pore glycoprotein p62, 62 kDa nucleoporin, Nucleoporin Nup62, NUP62, p62, IBSN, SNDI. | |
| Introduction | |
| Nucleopurin 62kDa (NUP62) belongs to the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. Nucleoporins are the principal components of the nuclear pore complex in eukaryotic cells. This complex is a colossal structure which extends across the nuclear envelope, forming an entryway that regulates the stream of macromolecules between the nucleus and the cytoplasm. NUP62 associates with the importin alpha/beta complex that is involved in the import of proteins containing nuclear localization signals. Defects in the NUP62 are the cause of SNDI (infantile striatonigral degeneration), aka infantile bilateral striatal necrosis (IBSN) or familial striatal degeneration. | |
| Source | |
| Sf9 insect cells. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| NUP62 is supplied in 20mM HEPES buffer pH-8, 200mM NaCl and 20% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as determined by SDS-PAGE. | |
| Applications | |
| Western blot with Polyclonal anti-Nup62 antibodies. | |
| Immunological functions | |
| 1. Binds IgG-type human auto-antibodies. 2. Standard ELISA test (checker-board analysis of positive/negative sera), immunodot analysis with positive/negative samples. | |
| Coating concentration | |
| 0.5-1.0 µg/ml (depending on the type of ELISA plate and coating buffer). Suitable for labeling of functional groups. | |
| Precautions | |
| NUP210 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q8TEM1 ) | |
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Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
