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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1596-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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| RCP1596-10 | 7 days | 10 µg | $290.00 | |||
| RCP1596-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | PCMTD1 Human |
|---|---|
| Description | |
| Protein-L-Isoaspartate O-Methyltransferase 1 Human Recombinant | |
| Accession (Primary) | Q96MG8 |
| Immunogen | |
| Anti-human PCNA mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PCNA amino acids 1-261 purified from E. coli. | |
| Synonyms | |
| Proliferating cell nuclear antigen, PCNA, Cyclin, MGC8367. | |
| Introduction | |
| PCNA is located in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps elevate the processivity of leading strand synthesis during DNA replication. In reaction to DNA damage, PCNA is ubiquitinated and takes part in the RAD6-dependent DNA repair pathway. 2 transcript variants encoding the same protein have been found for PCNA gene. Pseudogenes of this PCNA gene have been described on chromosome 4 and on the X chromosome. PCNA is expressed during late G1- phase, S-phase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA is induced by UV irradiation. | |
| Formulation | |
| 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. | |
| Applications | |
| The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| Pk1A3AT. | |
| Ig Subclass | |
| Mouse IgG3 heavy chain and κ light chain. | |
| Purification Method | |
| PCNA antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. | |
| Storage Procedures | |
| For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
| Stability / Shelf Life | |
| 12 months at -20°C. 1 month at 4°C. | |
| Precautions | |
| PCMTD1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q96MG8 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
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ADMEbio Team
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ADMEbio Team
