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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1605-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP1605-20 | 7 days | 20 µg | $290.00 | |||
| RCP1605-1 | 7 days | 1 mg | $5,280.00 |
Product Overview | |
| Name | PDCD1 Human, Active |
|---|---|
| Description | |
| Programmed Cell Death 1 Human Recombinant, Active | |
| Accession (Primary) | Q15116 |
| Immunogen | |
| Anti-human PDCD12 mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PDCD12 amino acids 254-362 purified from E. coli. | |
| Synonyms | |
| Cell death regulator Aven, AVEN, PDCD12, Programmed Cell Death 12. | |
| Introduction | |
| PDCD12 (AVEN) represents a new class of cell death regulator. PDCD12 is a conserved intracellular membrane protein which blocks apoptosis impeded by Apaf-1 mediated caspase activation. BAD and Bcl-2 also interact with PDCD12 to prevent apoptosis. PDCD12 is expressed in a wide variety of normal tissues including the heart, skeletal muscle, kidney, liver, testis, and also in diseases such as cancer. | |
| Formulation | |
| 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. | |
| Applications | |
| PDCD12 antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:1,000~1:2,000 and immunohistochemistry analysis is 1:50~100. Recommended starting dilution for Western blot is 1:1,000 and Immunohistochemistry is 1:50. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| P3G4AT. | |
| Ig Subclass | |
| Mouse IgG2a heavy chain and κ light chain. | |
| Purification Method | |
| PDCD12 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. | |
| Storage Procedures | |
| For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
| Stability / Shelf Life | |
| 12 months at -20°C. 1 month at 4°C. | |
| Precautions | |
| PDCD1 Human, Active is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q15116 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
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ADMEbio Team
