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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1616-5 | 7 days | 5 µg | $120.00 |
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| RCP1616-20 | 7 days | 20 µg | $290.00 | |||
| RCP1616-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | PDRG1 Human |
|---|---|
| Description | |
| p53 and DNA-Damage Regulated 1 Human Recombinant | |
| Accession (Primary) | Q9NUG6 |
| Immunogen | |
| Recombinant PDX1 E.Coli derived. | |
| Synonyms | |
| IPF1, IUF1, IDX-1, MODY4, PDX1, STF-1, Insulin promoter factor 1, Pancreas Duodenum Homeobox-1. | |
| Introduction | |
| PDX1 activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. IPF1 is particularly involved in glucose-dependent regulation of insulin gene transcription. Pancreas Duodenum Homeobox-1 binds preferentially the DNA motif 5'-[ct]taat[tg]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, it is required for maintaining the hormone-producing phenotype of the beta-cell. | |
| Stability | |
| Stable for 2 yeas at -20°C. Avoid freeze/thaw cycles. | |
| Applications | |
| Western Blot: 1:1,000 Immunohistochemistry: 1:500 Optimal working dilutions must be determined by end user. Routinely evaluated by western blot on lysates of rat pancreatic cell line INS-1 | |
| Type | |
| Polyclonal Rabbit Antibody. | |
| Specificity | |
| Human and Mouse PDX-1. | |
| Molecular Weight | |
| 35-40 kDa. | |
| Precautions | |
| PDRG1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9NUG6 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
