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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1627-5 | 7 days | 5 µg | $120.00 |
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| RCP1627-20 | 7 days | 20 µg | $290.00 | |||
| RCP1627-1 | 7 days | 1 mg | $5,760.00 |
Product Overview | |
| Name | PEX26 Human |
|---|---|
| Description | |
| Peroxisomal Biogenesis Factor 26 Human Recombinant | |
| Accession (Primary) | Q7Z412 |
| Synonyms | |
| CXCL4, PF-4, PF4, Iroplact, Oncostatin-A, SCYB4, MGC138298. | |
| Introduction | |
| Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets. Its major physiologic role appears to be neutralization of molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. Oncostatin-A is a member of the CXC chemokine family. Furthermore it is used as an inhibitor in the angiogenesis during tumor therapy. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered white lyophilized powder. | |
| Formulation | |
| The CXCL4 protein was filtered (0.2 µm) and lyophilized from a concentrated solution containing 20mM PB and 1.5M NaCl, pH 7.4. | |
| Stability | |
| Lyophilized CXCL4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL4 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY | |
| Biological Activity | |
| The biological activity determined by a chemotaxis bioassay using human fibroblasts is in a concentration of 1.0-10 ng/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized CXCL4 in sterile 18MΩ-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| PEX26 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q7Z412 ) | |
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ADMEbio Team
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