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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1634-5 | 7 days | 5 µg | $120.00 |
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| RCP1634-20 | 7 days | 20 µg | $290.00 | |||
| RCP1634-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | PFN1 Rat |
|---|---|
| Description | |
| Profilin-1 Rat Recombinant | |
| Accession (Primary) | P62963 |
| Synonyms | |
| Profilin-II, PFN2, Profilin-2, PFL, D3S1319E. | |
| Introduction | |
| PFN2 is a ubiquitous actin monomer-binding protein which is part of the profilin family. PFN2 regulates actin polymerization in response to extra cellular signals. PFN2 binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, while it increases it at low concentrations. PFN2 binds to PIP2, it inhibits the formation of IP3 and DG. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| PFN2 protein solution (1mg/ml) containing 20mM Tris-HCl pH-8, 1mM DTT and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MAGWQSYVDN LMCDGCCQEA AIVGYCDAKY VWAATAGGVF QSITPIEIDM IVGKDREGFF TNGLALGAKK CSVIRDSLYV DGDCTMDIRT KSQGGEPTYN VAVGRAGRVL VFVMGKEGVH GGGLNKKAYS MAKYLRDSGF. | |
| Precautions | |
| PFN1 Rat is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P62963 ) | |
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ADMEbio Team
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ADMEbio Team
