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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1637-2 | 7 days | 2 µg | $120.00 |
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| RCP1637-10 | 7 days | 10 µg | $290.00 | |||
| RCP1637-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | PGLYRP1 Human |
|---|---|
| Description | |
| Peptidoglycan Recognition Protein 1 Human Recombinant | |
| Accession (Primary) | O75594 |
| Synonyms | |
| PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L, Peptidoglycan recognition protein 1, peptidoglycan recognition protein short. | |
| Introduction | |
| Peptidoglycan Recognition Protein 1 (PGLYRP1) is a member of the N-acetylmuramoyl-L-alanine amidase 2 family. PGLYRP1 binds to peptidoglycan of bacteria and affects the peptidoglycan biosynthesis. PGLYRP1 displays bactericidal activity towards Gram-positive bacteria and is bacteriostatic towards Gram-negative bacteria. PGLYRP1 has a role in innate immunity. PGLYRP1 is highly expressed in the bone marrow, and weakly expressed in the kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils. | |
| Source | |
| HEK293 Cells. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| The PGLYRP1 solution (0.25mg/1ml) contains phosphate buffered saline (pH7.4) and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| DGSQETEDPA CCSPIVPRNE WKALASECAQ HLSLPLRYVV VSHTAGSSCN TPASCQQQAR NVQHYHMKTL GWCDVGYNFL IGEDGLVYEG RGWNFTGAHS GHLWNPMSIG ISFMGNYMDR VPTPQAIRAA QGLLACGVAQ GALRSNYVLK GHRDVQRTLS PGNQLYHLIQ NWPHYRSP HH HHHH | |
| Biological Activity | |
| Measured by its binding ability in a functional ELISA with Peptidoglycan. The ED50 range ≤ 30 ng/ml. | |
| Precautions | |
| PGLYRP1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( O75594 ) | |
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ADMEbio Team
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