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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1640-5 | 7 days | 5 µg | $120.00 |
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| RCP1640-20 | 7 days | 20 µg | $290.00 | |||
| RCP1640-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | PHB2 Human |
|---|---|
| Description | |
| Prohibitin 2 Human Recombinant | |
| Accession (Primary) | Q99623 |
| Synonyms | |
| PHD finger protein 11, BRCA1 C-terminus-associated protein, Renal carcinoma antigen NY-REN-34, PHF11, BCAP, APY, IGEL, IGER, IGHER, NYREN34, NY-REN-34, RP11-185C18.3. | |
| Introduction | |
| PHD finger protein 11 (PHF11) is a regulator of TH1-type cytokine gene expression. The decline in PHF11 expression observed with an AD-associated genotype may promote the intense TH2 reactions which characterize numerous allergic individuals. PHF11 is linked with raised total serum IgE levels, asthma and acute atopic dermatitis (AD) in children. Even though PHF11 includes a plant homeodomain, a motif frequently found in transcriptional regulators, PHF11 function of has yet been examined. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| PHF11 protein solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 85.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MAQASPPRPE RVLGASSPEA RPAQEALLLP TGVFQVAEKM EKRTCALCPK DVEYNVLYFA QSENIAAHEN CLLYSSGLVE CEDQDPLNPD RSFDVESVKK EIQRGRKLKC KFCHKRGATV GCDLKNCNKN YHFFCAKKDD AVPQSDGVRG IYKLLCQQHA QFPIIAQSAK FSGVKRKRGR KKPLSGNHVQ PPETMKCNTF IRQVKEEHGR HTDATVKVPF LKKCKEAGLL NYLLEEILDK VHSIPEKLMD ETTSESDYEE IGSALFDCRL FEDTFVNFQA AIEKKIHASQ QRWQQLKEEI ELLQDLKQTL CSFQENRDLM SSSTSISSLS Y. | |
| Precautions | |
| PHB2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q99623 ) | |
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ADMEbio Team
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