| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1650-2 | 7 days | 2 µg | $120.00 |
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| RCP1650-10 | 7 days | 10 µg | $290.00 | |||
| RCP1650-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | PI3 Human |
|---|---|
| Description | |
| Peptidase Inhibitor 3 Human Recombinant | |
| Accession (Primary) | P19957 |
| Synonyms | |
| Elafin, ESI, SKALP, WAP3, WFDC14. | |
| Introduction | |
| Peptidase Inhibitor 3, also referred to PI3, is neutrophil and pancreatic elastase-specific inhibitor of skin. The protein may prevent elastase mediated tissue proteolysis. PI3 has shown inhibition of alpha-4-beta-2/CHRNA2-CHRNB2 nicotinic acetylcholine receptor, a weak inhibition on Kv11.1/KCNH2/ERG1 and on the transient receptor potential cation channel subfamily V member 1. | |
| Source | |
| Sf9, Baculovirus cells. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The PI3 solution (0.2mg/ml) contains Phosphate-Buffered Saline (pH 7.4) and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 85.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| AVTGVPVKGQ DTVKGRVPFN GQDPVKGQVS VKGQDKVKAQ EPVKGPVSTK PGSCPIILIR CAMLNPPNRC LKDTDCPGIK KCCEGSCGMA CFVPQ HHHHH H | |
| Precautions | |
| PI3 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P19957 ) | |
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