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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1671-5 | 7 days | 5 µg | $120.00 |
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| RCP1671-25 | 7 days | 25 µg | $290.00 | |||
| RCP1671-1 | 7 days | 1 mg | $4,000.00 |
Product Overview | |
| Name | PMP2 Human, His |
|---|---|
| Description | |
| Peripheral Myelin Protein-2 Human Recombinant, His Tag | |
| Accession (Primary) | P02689 |
| Introduction | |
| PMSG Hormone is a well know used hormone together with progestogen to increase ovulation just before to artificial insemination. PMSG hormone is a placental glycoprotein produced from the serum of pregnant mares. PMSG comprises of an alfa subunit and a beta subunit. PMSG hormone is secreted from endometrial cups within the pregnant mare uterus aging from 40 to 130 days into their maturation, and once extracted, it can been used to promote artificially estrus in female animals. These assemblies produce PMSG hormone to induce mare's ovarian and repsouctive structures. PMSG can induce the growth of follicles by ovaries and results in ovulatation. PMSG hormone has an about a 4 day half-life of bioactivity in species other than horses. The extended biological activity can cause ovarian stimulation and ovulation. However, PMSG use alone often causes cystic ovarian disease because of the unrestrained ovarian stimulation and due to the sugar molecules which decrease clearance of the hormone. PMSG is more likely to be used than other pituitary hormones due to the extended circulatory half-life. PMSG solely exhibits luteinizing hormone like activity, however in other animal classes it has FSH & LH like activity. | |
| Source | |
| Serum of pregnant mares. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The PMSG was lyophilized with no additives. | |
| Stability | |
| Lyophilized PMSG although stable at room temperature for 3 weeks, should be stored between 2-8°C. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized PMSG in sterile 18M-cm H2O at a concentration of 1000 IU/ml, which can then be further diluted to other aqueous solutions. | |
| References | |
| 1. Title : REPRODUCTIVE CYCLICITY AND PROFILES IN POSTPARTUM RAMBOUILLET EWES TREATED CONTAINING INTRAVAGINAL INSERT AND PMSG . Publication : Proceedings, Western Section, American Society of Animal Science Vol. 62, 2011 Link : PMSG prospec publication 2. Title: Correlation of the Mitochondrial Activity of Two-Cell Embryos Produced In Vitro and the Two-Cell Block In Kunming and B6C3F1 Mice Publications: The Anatomical Record 292.5 (2009): 661-669. Link: Pregnant Mare Serum Gonadotropin prospec publication 3. Tröder SE, Ebert LK, Butt L, Assenmacher S, Schermer B, Zevnik B. An optimized electroporation approach for efficient CRISPR/Cas9 genome editing in murine zygotes. PloS one. 2018;13(5):e0196891. Epub 2018/05/04. doi: 10.1371/journal.pone.0196891. PubMed PMID: 29723268; PubMed Central PMCID: PMCPMC5933690. | |
| Precautions | |
| PMP2 Human, His is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P02689 ) | |
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